Klopp's men have made an encouraging start to their Bundesliga campaign, winning three successive matches including a 1-0 success over Werder Bremen last weekend.
BVB will go top with a win at Frankfurt, with Klopp admitting that his team will look to make a quick start to capitalise on the home side's involvement in the Europa League on Thursday.
He told reporters at a pre-match press conference: "We have an aim and that is to get a result which will earn us points, and that's how we've got to play.
"We are going there with an advantage and any advantage we have got must be made to count. I don't expect Frankfurt just to defend. They have a home game and I expect it to be intensive.
"They are a side who don't leave you much room and who get at you in tackles, and they are very strong from set-pieces."
Frankfurt come into the clash fresh from booking their place in the Europa League group stages in midweek, with a 2-1 win over Qarabag FK.