Blackpool failed to build on their first win of the campaign before the international break when they visited Huddersfield Town on Saturday, going down 4-2 in West Yorkshire after a calamitous start to the game.
Huddersfield were 3-0 up inside the opening 20 minutes and, although Blackpool pulled it back to 3-2, they couldn't pull off a miraculous comeback.
The Rams are now second in the table after Saturday's rousing 3-0 victory at Reading which extended their unbeaten run to nine games.
Steve McClaren named an unchanged side against the Royals, but he will be forced into changes at Bloomfield Road.
Derby won both games between the two last season and have also won five of their last six games against the Tangerines.
Possible starting lineups
Blackpool: Lewis, McMahon, Daniels, Clarke, J Oriol, Perkins, Lundstram, Cubero, E Oriol, Delfouneso, Miller
Derby: Grant, Christie, Keogh, Whitbread, Forsyth, Eustace, Hughes, Hendrick, Ibe, Martin, Russell
Sports Mole says: 0-2