Three points separate the two sides in the table, but both teams go into the contest looking to return to winning ways after recent setbacks.
With Jorge Jesus back at the helm, Benfica had made an ominous start to the new season after finishing as runners-up to Porto in both the league and cup last season.
Quickly putting the disappointing of failing to qualify for the Champions League group stages aside, the Eagles won their next seven games in a row across all competitions, scoring 22 goals in the process.
That included five wins from five to set the early pace at the top of the Primeira Liga, but their flying form came to a shuddering and wholly unexpected halt at the hands of an out-of-form Boavista side on Monday night as Benfica slipped to a 3-0 away defeat.
It looked as though that would be followed up by another unexpected loss in the Europa League on Thursday night when Nicolas Otamendi was sent off after only 19 minutes and Rangers raced into a 3-1 lead at the Estadio da Luz.
However, Jesus's side fought back to rescue a late 3-3 draw and preserve their unbeaten record in Group D - a stalemate which will have felt more like a win under the circumstances.
The challenge now is to prove that the loss to Boavista was an aberration of a result, and Braga will provide a stringent examination having chalked up four successive Primeira Liga wins heading into this one.
Carlos Carvalhal's side have responded well to surprisingly losing their opening two games of the season, and another triumph on Sunday would see them win five league matches in a row for the second time this calendar year.
Perennial top-four challengers, last season was the first time Braga had managed to break into the top three since 2011-12, and that will once again be the target this season.
However, for all of their good domestic form, Braga were handed a chastening lesson by Leicester City on Thursday night as the Foxes ran out 4-0 winners in their Europa League clash at the King Power Stadium.
Carvalhal will be demanding a response from his previously-perfect side this weekend, but an away trip to Benfica is about as difficult a challenge as you can get in Portuguese football at the moment.
Benfica Primeira Liga form: WWWWWL
Benfica form (all competitions): WWWWLD
Braga Primeira Liga form: LLWWWW
Braga form (all competitions): WWWWWL
We say: Benfica 2-1 Braga
This should be a fascinating game between two sides who had both been in excellent form before recent setbacks. Benfica will be demanding a response from their defeat at Boavista last time out and, with home advantage also in their favour, that is enough for us to lean towards last season's runners-up.