The reigning champions will enter the match against the team currently second in the table off the back of a 1-0 victory over Atletico Madrid on home soil last weekend.
Barcelona did not suffer any fresh problems during the match, but Inigo Martinez picked up a hamstring problem in the warm-up, and he is now set to be out until January.
Gavi will also be missing for the remainder of the campaign due to a serious knee problem.
Xavi is set to select the same XI that took to the field for the first whistle against Atletico, with Andreas Christensen expected to be the player to again benefit from Martinez's absence.
Barcelona possible starting lineup: Pena; Kounde, Araujo, Christensen, Cancelo; F de Jong, Gundogan, Pedri; Raphinha, Lewandowski, FelixNo Data Analysis info