Barcelona's injury woes have continued after they reveal that Frenkie de Jong and Memphis Depay suffered hamstring injuries while on international duty.
The Catalan giants already announced that Jules Kounde and Ronald Araujo picked up injuries while away with France and Uruguay respectively.
While Kounde is set to be out for around a month, Araujo is expected to miss the World Cup after electing to have surgery on a thigh problem.
Following the news of injuries for Kounde and Araujo, Barcelona have since confirmed that De Jong and Depay are also injured.
The pair were both forced off with hamstring issues in the Netherlands' 2-0 UEFA Nations League victory over Poland on Thursday.
With nine games to play in October, including the El Clasico during the middle of the month, Barcelona will hope that their injured players can make speedy recoveries.