Stefano Colantuono has been relieved of his job as the head coach of Atalanta BC.
The club's board have taken the decision following a run of four matches without a victory, which has seen the team slump to 17th in the Serie A standings.
La Dea have also moved quickly to replace the 52-year-old, with Edy Reja taking charge.
"Atalanta BC communicate that they have dismissed coach Stefano Colantuono, who will be replaced by Mr Edy Reja," read a statement on the club's official website.
"The club expresses profound admiration and gratitude to Mr Colantuono on account of the qualified work that he did with us for five years."
Reja's first game at the helm is due to be away at Parma on Sunday.