The League One side continued their eye-catching run in the competition two weeks ago when they surprised their Premier League opponents 3-1 in the first leg at Valley Parade.
Meanwhile, Villa will be looking to give an otherwise disappointing season some gloss by overturning the two-goal deficit in front of their home fans.
Paul Lambert is expected to name a strong side in order to avoid an embarrassment.
Bradford boss Phil Parkinson could restore a number of senior figures to his team having rested eight players for their recent Johnstone's Paint Trophy defeat to Crewe Alexandra.
Villa: Guzan; Vlaar, Clark, Bennett, Baker; Lowton, N'Zogbia, Westwood, Bannan; Agbonlahor, Benteke
Bradford: Duke; Darby, Dickson, McHugh, McArdle; Atkinson, Jones, Doyle, Gray; Hines, Wells
Sports Mole says: 2-0