In contrast, the visitors are in a rut and will be desperate to avoid a fourth straight defeat across all competitions this weekend.
A title charge is certainly not out of the question for this in-form Monaco side, who have started 2021 as they mean to go on with nine points from three matches.
Niko Kovac has overseen wins against Lorient, Angers and Montpellier since the turn of the year, during which his side have scored at least three goals in each game, although they were made to work for their victory over the latter last Friday.
Monaco stormed into a 3-0 lead courtesy of a Wissam Ben Yedder brace and Kevin Volland's 10th of the season, and even though Montpellier's Elye Wahi and Andy Delort both struck to set up a nervy finale, Kovac's men nevertheless held on for all three points at the Stade de la Mosson.
Volland has now been involved in 17 of Monaco's 39 goals this term, while Ben Yedder also boasts 14 contributions to his name despite contracting coronavirus earlier in the season, and the two prolific strikers are leading an unforeseen Monegasques title charge.
Only six points separate the free-scoring Monaco from leaders Paris Saint-Germain - the one team who can boast more goals than Les Monegasques' 39 so far - and they are now welcoming an out-of-sorts Marseille to a ground where they have only lost once all season.
In contrast, any prospects of Marseille challenging for glory are looking thinner by the week, and their rescheduled game against Lens in midweek ended in yet another defeat.
A victory would have seen Marseille sit just one point behind fourth-placed Monaco ahead of this game, but Simon Banza's header on the stroke of the hour mark propelled Lens to a much-needed victory in their surprise pursuit of a European place.
The pressure is mounting considerably on the shoulders of Andre Villas-Boas, who has seen his side pick up just one win from their last eight across all competitions, and that home defeat to Lens came only a few days after they had been put to the sword on their own turf by a relegation-threatened Nimes.
Ten points now separate Marseille from PSG and Lille - who have both played a game more - and even if Villas-Boas's men can rip up the form book and prevail at Monaco, they cannot rise any higher up the table just yet.
Furthermore, Les Olympiens have only taken one point from their last three away matches - a 0-0 draw with 19th-placed Dijon - although they did beat Monaco 2-1 at the Orange Velodrome earlier in the season.
Monaco Ligue 1 form: LWDWWW
Marseille Ligue 1 form: DLWDLL
Marseille form (all competitions): LWDLLL
Aleksandr Golovin is yet to start a game since returning from a serious hamstring injury, but Kovac could place his faith in the 24-year-old this weekend.
Marseille lost midfield lynchpin Boubacar Kamara to a muscular injury against Nimes and he will not return just yet, while Villas-Boas hopes to have Jordan Amavi back in time for the clash with Rennes on January 30.
The visitors recently rejected an offer from Aston Villa for midfielder Morgan Sanson, and Villas-Boas described the Premier League outfit's bid as "pathetic".
Monaco possible starting lineup:
Lecomte; Sidibe, Maripan, Badiashile, Henrique; Diop, Tchouameni, Fofana, Golovin; Ben Yedder, Volland
Marseille possible starting lineup:
Mandanda; Lirola, Gonzalez, Caleta-Car, Sakai; Gueye, Rongier; Thauvin, Sanson, Payet; Benedetto
We say: Monaco 3-1 Marseille
Volland and Ben Yedder are simply unstoppable for Monaco at the moment, and a reshuffled Marseille defence will be in for a taxing night at the Stade Louis II. The hosts' defence is not impenetrable, though, and the visitors should manage to get on the scoresheet, but Kovac's men simply boast too much attacking quality and are expected to march to a convincing win over their fellow European hopefuls.