Arsenal cannot afford to drop any more points in their remaining two Premier League games if they are to have any hope of finishing in the top four.
The Gunners have lost three top-flight matches in a row, conceding three goals in each of those, and find themselves two points behind Chelsea in the final Champions League spot.
Brighton & Hove Albion will be looking to take advantage of the fixture scheduling on Sunday afternoon, as they make the trip the Emirates Stadium in between their opponents' Europa League semi-final showdown with Valencia.
Here, Sports Mole looks at how Arsenal could line up for their final home match of the season.
As well as being without Ramsey, Suarez, Bellerin, Holding and Welbeck for the remainder of the season, Unai Emery must also make do without the suspended Maitland-Niles this weekend.
Koscielny is also a fitness doubt after leaving the field 10 minutes from time in the 3-1 first-leg win over Valencia on Thursday, so Emery may well have to tinker with his backline.
Right wing-back, or indeed right-back, is proving a particular problem for the Spaniard. Carl Jenkinson is favourite to get the nod for just his third Premier League start of the season, while Stephan Lichtsteiner - not used since February - is another option.
Matteo Guendouzi was surprisingly selected over Lucas Torreira in midweek, so the Uruguayan midfielder may return in midfield. Further forward, Alex Iwobi and Henrikh Mkhitaryan are well rested and offer alternatives to Alexandre Lacazette and Mesut Ozil if Emery wishes to keep things fresh.