The Gunners ended last season on a high after lifting the FA Cup, while Fulham also bring momentum into the new campaign following their promotion from the Championship.
The 2019-20 season will ultimately go down as a successful one for the Gunners thanks to that triumph, but a lot more is expected of them in the Premier League this time around.
Last term's eighth-placed finish was Arsenal's lowest since 1995, not helped by a return of four wins in their opening 13 fixtures, which they ultimately failed to recover from.
Arteta took over from Unai Emery midway through the season and, while results were largely mixed, the former Manchester City coach did not take long to make his mark on the field.
Arsenal played some impressive football at times and have carried that into this season, having already defeated champions Liverpool on pens in the Community Shield two weeks ago.
That may be little more than a glorified friendly to many, but it showed once again that the Gunners are now capable of holding their own against the division's top sides.
That is not exactly a category opponents Fulham fit into, of course, with the Cottagers preparing for their first season back in the top flight after a one-year absence.
Scott Parker achieved his mission of guiding the club back into the Premier League at the first attempt, although they had to do it the hard way by going through the playoffs.
A 2-1 win over bitter rivals Brentford on August 4 sealed a spot in the top division and Parker will now get his first proper shot at keeping Fulham in the division.
The Cottagers have played just one friendly since then, drawing 2-2 with MK Dons at the end of last month, despite Parker fielding a strong XI in the behind-closed-doors clash.
Arsenal also played the Dons and were far more comfortable, running out 4-1 winners in one of just two close-season outings for Arteta's charges.
As far as opening league fixtures go, this is one Arsenal supporters will surely be happy with given results between the sides down the years.
The Gunners have won each of their last five Premier League games against Fulham, scoring nine goals in their two wins the last time the West Londoners were in the top division.
Indeed, Arsenal have lost just one of their last 13 Premier League matches against Fulham (W8 D4), going down 2-1 at Craven Cottage in January 2012.
Fulham pre-season form: D
Arsenal pre-season form: WW
All three players will be pushing for inclusion here, but Robinson faces a tough task in ousting playoff final hero Joe Bryan, who scored both goals against Brentford.
Saliba and Willian are in line to make their debuts on Saturday, while Gabriel, who has barely trained since arriving, may also be called upon as David Luiz is carrying an injury.
Arteta has a big call to make in goal as Emiliano Martinez and Bernd Leno battle it out for the number one spot, while Eddie Nketiah's form for England Under-21s should see him get the nod through the middle.
Fulham possible starting lineup:
Areola; Odoi, Ream, Hector, Bryan; Lemina, Reed, Cairney; Knockaert, Mitrovic, Cavaleiro
Arsenal possible starting lineup:
Martinez; Saliba, Holding, Tierney; Bellerin, Ceballos, Xhaka, Maitland-Niles; Pepe, Nketiah, Aubameyang
We say: Fulham 0-2 Arsenal
Fulham have lost their opening game in their last two Premier League campaigns, while Arsenal are seeking successive matchday one victories for the first time since 2010.
The Gunners ended last season strongly and have carried that momentum into pre-season, so we are backing Arteta's men to make a winning start to this new campaign.
Top betting tipOur expert tipster partners at Sporita.com are predicting under 3.5 goals in this match. Click here to find out what else they are predicting for this game and for more of their tried-and-tested football tips.Under 3.5:data
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