Since this article was published, the derby has been called off due to a lack of players in the Arsenal squad. A new date for the game will be confirmed in due course.
Mikel Arteta's depleted side currently find themselves fifth in the rankings - one place and two points above Spurs, who have a game in hand - and here Sports Mole rounds up the team news for both clubs.
Sports Mole's predicted XI: Lloris; Tanganga, Sanchez, Davies; Emerson, Hojbjerg, Skipp, Winks, Sessegnon; Lucas, Kane
Out: Granit Xhaka (suspended), Martin Odegaard (COVID-19), Nicolas Pepe, Pierre-Emerick Aubameyang, Thomas Partey, Mohamed Elneny (all international)
Doubtful: Cedric Soares (hip), Takehiro Tomiyasu (calf), Emile Smith Rowe (groin), Sead Kolasinac (hamstring), Bukayo Saka (fatigue), Calum Chambers (knock)
Sports Mole's predicted XI: Ramsdale; Chambers, Holding, Gabriel, Tierney; Saka, White, Lokonga, Martinelli; Lacazette, Nketiah