The 20-year-old midfielder suffered a career-threatening leg break while playing against Stoke 20 months ago.
"I have no negative feelings towards Stoke," Ramsey said. "I've played against them since. It's just another game, what happened is in the past.
"I'm just looking forward to getting back out there and playing another game for Arsenal.
"Scoring against Marseille was a great moment for me and the club. We're in a great position and hopefully we can finish the job off in Europe."
Arsenal are currently 10th in the Premier League table, while Stoke sit in seventh place.