The Swans will be looking to pick up a result in North London after failing to win any of their last five Premier League matches.
However, Monk believes that his side's task has been made more difficult after Arsenal's 6-0 defeat to Chelsea on Saturday.
"It's a horrible feeling whenever you lose a game, but to lose by such a margin is hard to take," the Swansea boss told the South Wales Evening Post.
"I expect a good reaction from Arsenal. In football you always get that chance to put things right, and they will be thinking their game against us is that chance.
"Arsenal have a squad full of experienced, top professionals and international players, so I expect them to be back on their game tomorrow."
Swansea lost 3-2 at Everton on Saturday.