Austin Daye scored 22 points as the Spurs cruised past the Sixers, who have now gone 25 games without earning a win in the NBA.
Taj Gibson topped the scoring charts with 23 points as five Bulls players reached double figures to close the gap on the third-placed Toronto Raptors in the Eastern Conference.
Blake Griffin led the way with 27 points and 14 rebounds as the Clippers handed Milwaukee their 56th defeat of the campaign.
Butler came off the bench to score 23 points for the Thunder, while Durant added 27 points and eight assists.
Howard was forced to deal with Charlotte's fouling tactics on his way to 10 points and 10 rebounds, while Harden topped the scoring charts with 31 points.
Eric Bledsoe continued his good form with 20 points as the Suns benefited from a strong shooting display in Georgia.
Memhpis led throughout the contest and never looked back after building their first double-figure lead late in the first quarter.
After recovering from a 22-point deficit to level the scores at 98-98 at the end of the fourth quarter, Anthony Morrow scored with two three-point efforts in the extra period to help the Pelicans to the win.
Andre Drummond recorded 19 points and 14 rebounds for the Pistons, who won for the first time in Utah since 2002.
Results in full: Portland Trail Blazers 91-93 Miami Heat, Philadelphia 76ers 91-113 San Antonio Spurs, Indiana Pacers 77-89 Chicago Bulls, Milwaukee Bucks 98-106 Los Angeles Clippers, Denver Nuggets 96-117 Oklahoma City Thunder, Houston Rockets 100-89 Charlotte Bobcats, Phoenix Suns 102-95 Atlanta Hawks, Minnesota Timberwolves 92-109 Memphis Grizzlies, Brooklyn Nets 104-109 New Orleans Pelicans, Detroit Pistons 114-94