Powell finished with 29 points, Ibaka had 27 and 15 rebounds, while Pascal Siakam had 20 points and 10 assists.
The Raptors have been in crushing form since going into the NBA's bubble, going 11-1 in that time.
Caris LeVert scored 35 points for the Nets.
Kemba Walker led the way with 32 points, while Jayson Tatum added 28 points and 15 rebounds as the the Celtics pulled away in the fourth quarter.
Joel Embiid had 30 points and 10 rebounds for the 76ers while Tobias Harris had 20 points.
The Dallas Mavericks levelled their first round play-off series with the Los Angeles Clippers 2-2 with a thrilling overtime victory, winning 135-133 thanks to a Luka Doncic three-pointer on the final buzzer.
Doncic amassed 43 points, 17 rebounds and 13 assists to earn his second straight triple-double.
The Clippers had taken the lead with only nine seconds left thanks to a Marcus Morris three pointer, but Doncic would ruin their dreams of a 3-1 series lead.
Donovan Mitchell scored 51 points for Utah, while Jamal Murray had 50 for the Nuggets.
Mitchell took control to score 18 of his points in the gripping last quarter, and is now averaging 39.5 points per game in the series. Mike Conley contributed 26 points for Utah.
Murray hit a three-pointer moments from the buzzer to narrow the deficit.