The 30-year-old won many admirers during his stint as a professional that lasted 12 years.
So often when a famous sports man or woman calls it a day, their fellow competitors take to Twitter to pay tribute and it has been no different with Roddick.
Read what they have been saying below.
"Thank you @andyroddick for carrying American tennis so many years...with intensity, charisma, and grace. Phenomenal athlete, better person."
Zach Johnson, golfer
"True champion, longtime friend but most importantly one of the greatest people I have ever get to know leaves our sport!thanks @andyroddick."
Jurgen Melzer, tennis player
"@andyroddick I shed a tear for you. Thank you for all the years of commitment to excellence. Going to miss it."
Tiger Woods, golfer
"What a great champion of this great game, here's to you @andyroddick !!!"
Matthew Ebden, tennis player
"Congratulation @andyroddick for your great career and for the great person you've been during the tour!"
Juan Monaco, tennis player
"Congrats to @andyroddick for an amazing carrer!! We gonna miss you in the court !! #LEGEND."
Christian Lindell, tennis player
"Congrats to @andyroddick for an amazing career. Class act. #respect."
Abby Wambach, footballer
"In tears listening to @andyroddick right now...what an unbelieble careear and personality."
Gisela Dulko, tennis player