Rather than being nervous about the match, Robson has insisted that she will be going out to beat her Belgian opponent.
"It's really exciting [to be playing Clijsters]," she told BBC Sport. "Ever since I've been on the Tour, she's always been extremely nice to me, so it's great to finally play her. But I'm looking to win."
Robson has never gone beyond round two at Flushing Meadows.