The Red Dragons saw their match at Aldershot Town on Saturday abandoned in the second half due to a waterlogged pitch, while Chesterfield suffered a 3-1 loss at Woking in their last league fixture.
Goals from Jake Hyde and Paul Mullins saw Wrexham take a 2-0 lead at Aldershot on Saturday, but referee Sunny Gill blew what proved to be the final whistle in the 52nd minute due to a waterlogged pitch.
Wrexham players had attempted to sweep the rain away from the pitch, but the worsening conditions meant that the fixture had to be abandoned, with the contest set to be replayed at another time.
There was clear frustration for the Red Dragons, but the hosts have to dust themselves down and prepare for Tuesday's clash at home to Chesterfield, where they will be looking for a fourth league win of the campaign.
Indeed, a record of three wins, three draws and two defeats from their opening eight matches has seen them collect 12 points to sit 11th in the table.
Chesterfield, meanwhile, have not been in action since suffering a 3-1 defeat at Woking on September 28, with the loss proving to be their first in the National League this season.
A record of five wins, three draws and one loss from nine matches has seen them collect 18 points, which has left them third in the table, just two points behind leaders Grimsby Town on the same number of games.
James Rowe's side finished sixth in the National League last season, qualifying for the quarter-finals of the playoffs in the process, but they suffered a 3-2 defeat to Notts County.
The Spireites will be expecting to challenge high up the division this term, and a win at Wrexham on Tuesday would lead them nicely into a trip to a struggling Southend United on October 9.
Wrexham boss Parkinson is expected to name close to the same starting XI that took to the field for the clash with Aldershot on Saturday.
As mentioned, goals from Hyde and Mullins had left the visitors two goals ahead, and it seems unlikely that the Red Dragons manager will make many changes to the side that featured from the first whistle.
Luke Young and Ben Tozer were both replaced in the first half of the contest, though, and have therefore emerged as injury doubts, with Tyler French and Devonte Redmond on standby to come into the team.
As for Chesterfield, head coach Rowe could make changes from the side that started the 3-1 defeat to Woking in Surrey last time out.
Kabongo Tshimanga is the leading goalscorer in the National League this season with nine, though, and the 24-year-old is a certainty to start for the visitors.
Wrexham possible starting lineup:
Lainton; Hayden, French, Lennon, Hosanah; Redmond, Jones, Davies, Reckord; Hyde, Mullins
Chesterfield possible starting lineup:
Loach; Kerr, Grimes, Gunning; King, Khan, Rowe, Weston, Miller; McCourt, Tshimanga
We say: Wrexham 1-1 Chesterfield
Both sides will believe that they are capable of hurting the other in the final third of the field, and it should be a fascinating battle on Tuesday night. Wrexham will be looking to overcome Saturday's disappointment, but Chesterfield must be taken seriously at this level, and we have had to settle on a low-scoring draw.