The game could not have started any better for the home side, as after a solid early spell of possession Ricardo Rodriguez picked out Ivan Perisic from a free kick and the winger made no mistake with his header.
Ivica Olic then had a chance on 10 minutes to double the advantage, but he could only get underneath the ball from a Kevin de Bruyne corner and sent his effort over the bar.
The home side continued to control proceedings but there were few real clear-cut efforts on goal, as Maximilian Arnold drilled a shot from the edge of the box narrowly wide.
Not long after the break Perisic forced Oliver Baumann into a fine save, with the goalkeeper tipping over the bar as the pressure remained on the visitors.
Wolfsburg managed to get themselves back on top with a fine low finish from Perisic, but Freiburg came forward once more and grabbed a late leveller with Marco Terrazzino's finish from the corner of the six-yard box.