The Hammers have been dragged back into the battle for survival in recent weeks thanks to a disappointing string of results.
In contrast, four wins in their last six matches have seen Hull pushing for a top-half finish heading into the final weeks of the season.
The Tigers make the trip to East London in 12th place in the table, four points behind 10th-placed Stoke City.
Matt Jarvis will face a late fitness test for West Ham, but Joey O'Brien and Marco Borriello are both unavailable through injury.
West Ham: WWWLLL
Possible starting lineups
West Ham: Adrian; McCartney, Tomkins, Collins, Demel; Nolan, Taylor, Noble, Diame, Downing; Carroll
Hull: McGregor; Rosenior, Davies, Chester, Elmohamady; Meyler, Huddlestone, Livermore; Jelavic, Long, Aluko
Sports Mole says: 1-2