The duo will start either side of main striker Yevhen Seleznyov as Ukraine chase a first-leg lead against a team they have never beaten in four previous attempts.
Slovenia, meanwhile, have made four changes from their last qualifier against San Marino.
Ukraine: Pyatov; Fedetskiy, Khacheridi, Rakitskiy, Shevchuk; Rybalka, Sydorchuk, Garmash; Yarmolenko, Konoplyanka; Seleznyov
Subs: Boyko, Shevchenko, Pylyavskyi, Kamenyuka, Tymoshchuk, Petriak, Malinovskiy, Gusev, Karavayev, Budkivskiy, Gladkiy, Kravets
Slovenia: Handanovic; Brecko, Ilic, Cesar, Jokic; Kurtic, Krhin, Kampl, Birsa; Ilicic, Novakovic
Subs: Oblak, Vidmar, Andjelkovic, Samardzic, Andraz Struna, Lazarevic, Kirm, Rotman, Pecnik, Verbic, Ljubijankic, Bezjak