The defender, who is on loan from Tottenham Hotspur, played the whole 90 minutes in the draw at Bolton Wanderers despite being unwell but manager Brendan Rodgers says that the player will be ready for Saturday.
"How he got through the Bolton game I don't know, because he had been up all night," revealed Rodgers.
"He had flu, so for him to be out on the field was incredible. He is going to be a top player and performances like that show why."
Caulker has made 23 appearances for the Welsh club this season.