The frontman makes his full return from injury having come on as a substitute against Chelsea last weekend, in one of four changes from that game as Spurs aim for a sixth successive league victory.
Mame Biram Diouf is able to take his place from the start having shaken off a calf injury that saw him come off at the Emirates, while Kurt Zouma is fit enough to make the bench following a knee problem.
Charlie Adam, meanwhile, remains absent as he serves the third of a three-match suspension.
Stoke City: Butland; Johnson, Shawcross, Martins Indi, Pieters; Bauer, Allen, Ndiaye, Diouf, Shaqiri; Sobhi
Subs: Haugaard, Zouma, Ireland, Cameron, Fletcher, Crouch, Campbell
Tottenham Hotspur: Lloris; Aurier, Sanchez, Vertonghen, Rose; Wanyama, Dembele; Eriksen, Alli, Son; Kane
Subs: Vorm, Davies, Dier, Sissoko, Lamela, Lucas, Llorente
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