In terms of matters on the field, Tottenham head into the clash as favourites due to their record of four wins in six encounters, which has placed them third in the Premier League table, two points adrift of leaders Arsenal.
It's a different story for West Ham, though, who have been struggling for firepower due to the long-term absence of striker Andy Carroll, resulting in their failure to win a game since their opening-day 2-0 win over Cardiff City.
Manager Sam Allardyce is expected to name Joe Cole on the bench following a stint on the sidelines with injury, while Spurs boss Andre Villas-Boas is likely to make a number of changes to the team that defeated Anzhi Makhachkala 2-0 in the Europa League on Thursday.
Tottenham Hotspur: WWLWWD
West Ham United: WDLDLL
Possible starting lineups
Tottenham Hotspur: Lloris; Walker, Naughton, Dawson, Vertonghen; Paulinho, Dembele; Townsend, Eriksen, Sigurdsson; Soldado
West Ham United: Jaaskelainen; O'Brien, Tomkins, Reid, Rat; Morrison, Diame, Noble, Jarvis; Nolan; Petric
Sports Mole says: 2-0