Southampton will be keen to build on the point they picked up away to league leaders Chelsea last time out, while Sean Dyche's Burnley will want to pick up where they left off in beating champions Manchester City last Saturday evening. Three points would be huge for them this afternoon, with the team still in the thick of the relegation battle with just two months of the season remaining.
One change for the Saints then, with Italian forward Graziano Pelle returning the starting eleven in place of midfielder Victor Wanyama. It means that Ronald Koeman's side will likely lineup in a 4-4-2 formation today, with Pelle partnering Shane Long up front. Koeman opted to drop Pelle for his team's game at Chelsea last weekend - the striker having been unable to find the back of the net as yet in 2015.
For Burnley, striker Sam Vokes starts for the second game in a row alongside Danny Ings in an unchanged lineup. The Welsh forward was recalled for international duty during the week - a clear sign that he is reaching peak fitness after his long injury problem.
The Saints were well worth their point against Chelsea last Sunday after a first half in which they created a number of very good opportunities. Dusan Tadic's penalty levelled the match, but Sadio Mane and Long both squandered chances, finding Blues stopper Thibaut Courtois in fine form. While Jose Mourinho's men had the upper hand after the break, Koeman's team deserved to travel home with something from the game.
As for Burnley, their tails will surely be up after taking the scalp of Manchester City on their own patch. George Boyd's left-footed half volley was enough for them to claim the win, and they now sit just a point back from Sunderland in 17th.
Dyche will know only too well that his team's form away from Turf Moor is poor though, with just one victory all season to their names. Today represents another tough match for Burnley, but they did manage a draw at Chelsea themselves just last month.
When these two met in December, Barnes' strike was the difference as Burnley took the three points. A late rally almost saw the Saints level, but Dyche's men held on and got their win. A repeat today would really put pressure on Dick Advocaat's Sunderland, who aren't in action until later this evening away to West Ham United.
PREDICTION! So Matt thinks Burnley are able to get a point from this one, though I'm not so sure and I'm going to side with Pascal and go for a home win. I'm also backing Pelle to get back amongst the goals today, and I think that Koeman's men will dispatch the Clarets with relative ease in a 2-0 victory.
We're just a few minutes away from kickoff here then, and both sides are out on the pitch. Southampton of course are kitted out in their traditional red and white stripes, while the away side lineup in all black.
Bertrand skins Trippier down Southampton's left and Duff clears the ball for a corner. When the resulting set piece comes in, it finds Schneiderlin on the edge of the area - his wild attempt sailing into the crowd.
The home side are unsurprisingly the ones showing the attacking ambition in the early stages, with them keen to get down that left side as often as possible. Already, Tadic and Schneiderlin are keen to find the forwards quickly too.
INJURY! Fraser Forster is down on the deck, holding his arm up and looking in a bad way. This is a strange one, because as the keeper kicks the ball clear, his ankle is tapped by Sam Vokes, and although it doesn't look too sinister, he's clearly in pain.
Straight away, Forster knew he was in trouble. I think his foot gets jarred in the turf and although their was very slight contact from Vokes, it wasn't in any way his fault. The stretcher is on and Forster is going to be replaced.
Half a chance for Pelle, who looks rusty as the ball reaches him. Bertrand and Long combine well, and the striker plays the Italian in. When it looks as if he should hit it first time, he cuts back into trouble and Burnley are able to clear.
Great defending from Southampton when Ings looks like he's going to get a shot at goal. He's played in by a nice ball from the left, but it results in Alderweireld ushering him away from a dangerous position.
Burnley should definitely have a penalty here. Arfield finds Boyd, who feints to shoot, turns inside and is promptly hacked down by Fonte. It should be a spot kick, in my opinion, so the Saints have got away with one there.
Perhaps contact isn't as heavy as I'd have thought but Boyd is certainly touched by Fonte. Shortly after, Ings goes down in the box under Fonte's tackle again, though this time a penalty would've been incredibly harsh.
BLOCK! Up the other end, Mane whips the ball into the box which Boyd can only clear as far as Schneiderlin. The Frenchman shoots, but Shackell gets his body in the way to deflect the ball for a corner.
Burnley are very much in this game today, and I've really enjoyed their willingness to go forward as quickly as possible. Dyche certainly hasn't come to St Mary's with a "settle for a point" mentality, which is great to see.
The home side open the scoring, via the left boot of Shane Long at the back post. After Mane had a header blocked, the ball worked it's way to Nathaniel Clyne. The right back drills the ball into the area, Pelle swings for it and misses, and eventually it reaches Long. The Irishman shows great composure, lifting the ball past Heaton and into the net.
CHANCE! Southampton go close again, with Pelle rattling the crossbar after Heaton had blocked a goalbound header from a free kick. With the hosts ruing their luck that their lead isn't doubled, Burnley break and Ings forces a brilliant stop from Davis. Great game this now.
CLOSE! Another near miss, this time from the home side. Clyne drills another ball into the box from a distance, though this time he is shooting. It takes two deflections, and Heaton is happy to see it dribble just wide of his post.
SAVE! Excellent tipped save from Heaton, whose diverts Steven Davis' header over the top. Tadic's ball was a great one, Davis got his header away before being clattered by his own man Pelle, and somehow Heaton's fully stretched arm keeps the score at 1-0.
SAVE! This is incredible now, as Kelvin Davis is forced to make another save of his own. Barnes heads the ball across goal to set up Vokes and his own header is aimed at goal. It's close, but it's straight at Davis really. Still, it needed to be stopped.
Well, what a brilliant half of football that was - I'm grateful to get my breath back! The two sides have mustered 17 shots between them, and what we've found today is two keepers in great form. Both Tom Heaton and Kelvin Davis have made impressive stops, though frankly I'm not sure how it's only 1-0.
At the other end, Pelle has struggled with the bits and pieces that have reached him. First, he took one too many touches in the box, before swinging and missing the ball which eventually found Long to score the opener. Finally, his effort which hit the bar really should have gone in, but at least he's getting into the right positions.
This second half is a little bit calmer than the way things were towards the end of the first period. Still, it's clear that Burnley aren't going to roll over and give up salvaging something from this game today.
CLOSE! Southampton play the ball upfield, with Shackell beating Pelle to it in the air. The knockdown falls to Long who takes a touch and then cannons an effort goalwards. Heaton is at full stretch once more, but this time doesn't make a save as the ball fizzes wide.
The Saints work the ball down the left and Davis scoops it to Bertrand. The left back hammers a dangerous ball into the six yard box and Shackell reacts, sticking out a knee. It cannons off him and past Heaton before the keeper can even blink. Game over?
SUBSTITUTION FOR BURNLEY: Vokes comes off for Jutkiewicz. Apologies, I'd lost my connection there briefly. While away, Pelle had a header saved by Heaton and Ings almost closed down Kelvin Davis to nick the ball to score.
Southampton win a free kick just outside the box, when Arfield blocks a Mane shot with his hands. The fans want a penalty but it's not in the box from where I'm watching. Alderweireld tries to bend it into the far corner but it's slightly too high. Not the worst effort.
Pelle is a man desperate to break his 2015 duck here. Every time he gets it, he's keen to get a shot off if half a chance is presented. This time, he unleashes a speculative left footer towards goal when Davis is probably in a better position. The fans moan a little, but I feel sorry for him to be honest.