Keller begins his first full campaign under pressure to deliver Champions League football for a third straight season.
He told reporters: "We're in front of our own fans and, with them behind us, we want to win this game."
Keller also confirmed that Jefferson Farfan has recovered from a virus to enter his plans for tomorrow's match.
He said: "Farfan is definitely going to start."
Schalke finished fourth in the Bundesliga last season, earning a Champions League qualifier against Metalist Kharkiv after a fine end to the campaign under Keller.