After back-to-back losses, the visitors have fallen back into the bottom three of the Primeira Liga table, currently occupying the relegation place with a two point gap between themselves and automatic safety.
Santa Clara suffered a narrow defeat last time out, when the travelled to take on third-placed Benfica.
While that was not an overly disheartening result for Daniel Ramos's side, it did stretch their winless run to three games in the top flight, having previously lost 1-0 to Vitoria de Guimaraes and drawn 0-0 with Moreirense.
As a result, Os Acoreanos have fallen behind both Vitoria and Moreirense, now sitting in eighth spot with just a one-point lead over ninth-placed Tondela.
Ramos will be hopeful of his side stopping their decline on Saturday, as they look to earn back their place in the top six with the end of the season approaching.
They take on a Boavista side who need a win for different reasons, as they look to climb out of the bottom three.
Jesualdo Ferreira's men come into this game on the back of consecutive defeats, having lost 1-0 in an important game at home to fellow strugglers Maritimo last time out.
While they did previously climb out of the drop zone with a run of two wins and a draw from their first three games in April, As Panteras have since fallen back into danger following those last two defeats.
Now occupying the relegation place, Boavista sit just two points above the automatic drop zone, meaning they could quickly be dragged back into the bottom two.
However, they remain just two points adrift of automatic safety, and Ferreira will be encouraged by the fact that they could jump back out of the bottom three with a win on Saturday.
Santa Clara will remain without centre-back Fabio Cardoso, who will serve the second match of his two-game suspension, having accumulated 10 domestic yellow cards this season.
However, Costa will be pushing for a return, as the attack has looked noticeably less threatening in his absence.
Boavista will be boosted by the return of centre-back Jackson Porozo, after he served a suspension last time out for a red card shown in the defeat to Braga.
At the other end of the pitch, the forward line of Yusupha Njie, Alberth Elis and Angel Gomes should offer plenty of threat, with the players registering a combined four goals and three assists in the last four league outings.
Santa Clara possible starting lineup:
Marco; Ramos, Afonso, Villanueva, Mansur; Lincoln, Morita, Carvalho; Carlos, Costa, Allano
Boavista possible starting lineup:
Leonardo; Devenish, Rami, Awaziem; Cannon, Santos, Cafumana, Sauer; Gomes, Elis, Njie
We say: Santa Clara 1-2 Boavista
With the battle for survival heating up, we see Boavista galvanising to pick up a crucial victory on Saturday.
The hosts have dipped in form in recent weeks, and could get caught out at home by a resilient Boavista outfit who will be desperate to bounce back from consecutive top-flight defeats.