Rudi Garcia has made three changes to his Roma side for tonight's must-win visit of Empoli at Stadio Olimpico.
Seydou Keita has returned from Africa Cup of Nations duty with Mali to replace Daniele De Rossi, while Miralem Pjanic also comes in for the injured Kevin Strootman in a double midfield alteration.
Elsewhere, right-back Maicon replaces Alessandro Florenzi in the final change from last week's 1-1 draw with Fiorentina.
Francesco Totti, Juan Manuel Iturbe and Adem Ljajic form a three-pronged attack as the Giallorossi look to move within four points of Serie A leaders Juventus, who play Udinese tomorrow.
Roma: De Sanctis; Maicon, Manolas, Mapou, Cholevas; Pjanic, Keita, Nainggolan; Ljajic, Totti, Iturbe
Empoli: Sepe; Barba, Rui, Hysaj, Rugani; Saponara, Validfiori, Croce, Vecino; Maccarone, Pucciarelli
Shane Callaghan
