Hubert Fournier has opted to make three changes to the Reims side that beat Sochaux on the road in their last match.
Christopher Glombard, Mickael Tacalfred, Atila Turan have all dropped out of the starting lineup, while Mohamed Fofana, Franck Signorino and Gaetan Charbonnier all come into the team.
Meanwhile, Claude Puel has also made three alterations following Nice's home loss to AS Monaco on Tuesday.
Kevin Gomis, Fabrice Abriel and Valentin Eysseric have all been demoted to the bench and replaced by Luigi Bruins, Gregoire Puel and Nemanja Pejcinovic.
Reims: Agassa, Fofana, Mandi, Signorino, Weber, Albaek, Krychowiak, Oniangue, Ayite, Charbonnier, De Preville
Nice: Veronese, Bodmer, Genevois, Kolodziejczak, Pejcinovic, Puel, Bruins, Bruls, Digard, Mendy, Cvitanich
Matt Cotton
