Getafe started the stronger side and Paco Alcacer had a couple of chances inside the opening 10 minutes. His first shot was blocked before he fizzed a free kick just wide.
Valladolid started to get on top of the game as Daniel Larsson had two efforts saved by Jordi Codina.
However, it was the visitors who got the opening goal on the stroke of half time as Alcacer nodded a Borja cross into the bottom corner.
After the break Valladolid piled forward and it was the lively Oscar who finally got the goal, slamming in a header from Alvaro Rubio's cross.
Then four minutes later Javi Guerra scored the winner having been set up by Oscar.