Shola Ameobi will lead the Bolton attack, while Gary Madine starts on the substitutes' bench.
French defender Prince-Desir Gouano will feature for the Trotters, despite being in Paris when the terrorist attacks occurred last week.
Reading: Al-Habsi; Gunter, Taylor, Hector, McShane; Norwood, Piazon, Williams; Blackman, McCleary, Sa
Subs: Bond, Vydra, Obita, Hurtado, John, Cooper, Liburd
Bolton Wanderers: Amos; Vela, Wheater, Prince, Casado; Spearing, Danns, Pratley, Davies; Feeney, Ameobi
Subs: Rachubka, Dervite, Clayton, Madine, Heskey, Wilson