Harry Redknapp's side were relegated last season despite spending big to try to maintain their top-flight status, but several of their star names are unlikely to feature against Wednesday at Loftus Road.
Loic Remy, Julio Cesar and Joey Barton could all sit out as they await moves away from the club, but striker Charlie Austin is expected to make his Hoops debut after arriving in a £4m switch from Burnley.
Fellow summer arrivals Richard Dunne and Danny Simpson are in contention to start in defence, while former Wolverhampton Wanderers captain Karl Henry is in the squad but may have to settle for a place on the bench.
However, the game may have come too early for ex-Hull City centre-back Kamil Zayatte, who completed his move to Hillsborough only on Friday.
The visitors finished 18th in the Championship last season, and retaining the services of top goalscorer Michail Antonio may have been Jones's best piece of summer business.
QPR: Green; Simpson, Dunne, Hill, Traore; Wright-Phillips, Jenas, Mbia, Hoilett; Zamora, Austin
Wednesday: Kirkland; Reda Johnson, Gardner, Taylor, Llera; Antonio, Jermaine Johnson, Maghoma, Prutton, Helan; Madine
Sports Mole says: 2-0