Jordan Pickford makes his first league start for Preston North End as they face Middlesbrough on their return to the Championship.
Greg Cunningham and Marnick Vermijl also make their full debuts for Lilywhites, while the club's top scorer last season, Joe Garner, also features at Deepdale.
Will Keane is given a first start by North End boss Simon Grayson since his move from Manchester United
Stewart Downing features for Boro as he begins his second spell at the club after leaving West Ham United.
Christian Stuani is on the bench for Aitor Karanka's men after receiving his international clearance, but Ben Gibson misses out with injury.
Preston North End: Pickford, Vermijl, Clarke, Huntington, Wright, Cunningham, Welsh, Johnson, Gallagher, Keane, Garner
Middlesbrough: Konstantopoulos, Kalas, Ayala, Fry, Friend, Adomah, Clayton, Leadbitter, Reach, Downing, Kike
Chris O'Keefe
