On the other hand, the visitors come into the contest off the back of consecutive defeats and will be looking to arrest this slump in form.
PEC Zwolle suffered a fourth straight defeat on the road following a comprehensive 5-1 win for Utrecht when the teams faced off on Saturday.
The Blauwvingers remain rooted to the bottom of the Eredivisie table, four points adrift of safety with the season still in its opening quarter.
They will hope to turn things around against an opposing side who they beat in both of last season's league meetings by a combined score of 6-1.
However, Saturday's hosts did fall to a 2-0 defeat in the most recent encounter involving the outfits, which was a pre-season friendly back in July.
In search of a second home win on the trot, Heerenveen were defeated 3-2 by Twente in a frenetic affair at the Abe Lenstra Stadion on Sunday.
Goals from Ricky Van Wolfswinkel and Daan Rots saw Johnny Jansen's men trail by two at half time, before a Sven Van Beek own goal looked to have been the final nail in the coffin, but Heerenveen nearly forced a draw courtesy of a Henk Veerman strike and a Robin Propper own goal.
With 10 points from seven outings so far, De Superfriezen are eighth in the Eredivisie as things stand, 10 places and nine points better off than their next opponents.
Saturday's visitors follow up this weekend's contest with games against two of the current top five and will be keen to secure a confidence-boosting victory ahead of those matches.
Rami Kaib made his return to action with a second-half cameo versus Twente last time out, but he could be given the nod right from the off this time around.
Sai Van Wermeskerken remains out of action for Zwolle since picking up a knee injury in February, and the Japanese defender continues his spell on the sidelines.
PEC Zwolle possible starting lineup:
Lamprou; Pabai, Van Polen, Kersten, Nakayama; Reijnders, Strieder, Van den Belt; Paal, Tedic, Redan
Heerenveen possible starting lineup:
Mulder; Dresevic, Woudenberg, Van Beek, Van Ewijk; J.Veerman, Halilovic, Madsen; De Jong, H.Veerman, Musaba
We say: PEC Zwolle 1-2 Heerenveen
Zwolle have found it hard to get going at both ends of the pitch, and it is hard to see things changing this weekend. We predict that the visiting team will come away with all three points.