The 62-year-old will leave the Dutch national team following this summer's tournament in Brazil.
Having already managed in Holland, Spain and Germany, Van Gaal is now ready to try his luck in England and add to his list of honours.
"My ambition is to coach a top team in the Premier League. I have never experienced the atmosphere in England," he told Bild.
"I want to win the league title in a fourth country. That's my objective and I want to fulfil it. Either that, or I will retire and move with my wife to Portugal."
Van Gaal has won a host of honours, including six league titles, the Champions League and the UEFA Cup, during his 28-year managerial career.