The two forwards, both of whom were involved at the World Cup for Egypt and Senegal respectively, came off the bench against Manchester City in midweek.
Jurgen Klopp has now named the duo in his starting XI, lining up in attack alongside young striker Dominic Solanke, while academy youngster Kamil Grabara is named in goal.
Xherdan Shaqiri joined up with the squad this week and has been named on the bench, but Nathaniel Clyne flew home on Thursday due to family reasons and Naby Keita and Georginio Wijnaldum are out injured.
Man United, meanwhile, have named Fred on the bench, the Brazil international joining up with the rest of the United squad on Wednesday.
Andreas Pereira, Ander Herrera and Scott McTominay start as the midfield three, while Juan Mata will operate behind Alexis Sanchez in the final third.
Nemanja Matic, Diogo Dalot, Sergio Romero and Antonio Valencia are not involved due to injury, however, while Anthony Martial flew home for the birth of his child.
Manchester United: Grant, Darmian, Fosu-Mensah, Smalling, Tuanzebe, Mitchell, McTominay, Pereira, Andreas, Mata, Sanchez
Subs: Pereira, Shaw, Williams, Chong, Fred, Garner, Gomes, Hamilton, Greenwood
Liverpool: Grabara, Camacho, Klavan, Van Dijk, Moreno, Fabinho, Lallana, Milner, Salah, Mane, Solanke
Subs: Kelleher, Gomez, Sturridge, Grujic, Shaqiri, Robertson, Origi, Phillips, Jones, Markovic, Ojo, Woodburn, Chirivella
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