Manchester United have problems in the middle of their defence ahead of Tuesday's Premier League clash with Nottingham Forest at Old Trafford.

Casemiro had to play alongside Victor Lindelof in central defence against Burnley in the EFL Cup on Wednesday, with Harry Maguire missing through illness, and both Lisandro Martinez and Raphael Varane given time off following their involvement in the World Cup final.

Man United are hopeful that Maguire will be back from illness in time for this match, while Martinez and Varane could potentially both be in the squad despite not yet returning to Carrington.

Axel Tuanzebe is still out through injury, while Diogo Dalot is a major doubt with the problem that he picked up while representing Portugal at the 2022 World Cup.

As a result, Aaron Wan-Bissaka could potentially make just his second Premier League appearance of the season, with Luke Shaw featuring on the opposite side.

There is a strong chance that Man United will be without three of their usual back four, but aside from Jadon Sancho, the team are in good shape going forward.

Antony came off the bench against Burnley on Wednesday and is now pushing to feature in the XI, with Marcus Rashford potentially moving across to the left.

Anthony Martial appears to have overcome his fitness problems, meanwhile, and the France international should again lead the line in this contest.

Manchester United possible starting lineup: De Gea; Wan-Bissaka, Lindelof, Maguire, Shaw; Casemiro, Eriksen; Antony, Fernandes, Rashford; Martial