While it certainly does not make up for being dethroned as champions of England, the City faithful would have been enraptured by their side's 4-0 drubbing of Liverpool on Thursday as Pep Guardiola's men condemned the holders to just their second league defeat of the season.
The Citizens are all but assured of their second-placed finish in the top flight and can now turn their attention to their FA Cup and Champions League campaigns, but Guardiola will not want his players to rest on their laurels as the Premier League season draws to a close.
With that in mind, Sports Mole looks at how City could line up for the clash with Southampton on Sunday.
Out: Sergio Aguero (knee)
The infamous Pep rotation is likely to strike again as City contend with a hectic fixture schedule, but Guardiola may be reluctant to make too many changes to the team that swept aside Liverpool with ease in midweek.
Sergio Aguero is the only confirmed absentee for the Citizens, who will also welcome Fernandinho back to the team after the Brazilian served a two-game suspension.
Fernandinho could come straight back into the starting XI alongside Aymeric Laporte in the heart of defence, and Guardiola has plenty of options in the full-back positions should he look to rest Kyle Walker and Benjamin Mendy.
Phil Foden's performances have given every England fan a reason to get excited for future international competitions, and the 20-year-old's starring role against Liverpool should see him rewarded with another start against Southampton.
Up top, Riyad Mahrez is in line to feature on the right-hand side with Raheem Sterling occupying the left flank, and while Gabriel Jesus failed to find the back of the net against Liverpool, the Brazilian is expected to spearhead the attack in Aguero's absence once again.
However, Bernardo Silva is another option up front for Guardiola - with the Portuguese having been utilised as a false nine against Chelsea and capable of playing in a number of roles in the final third.