The Premier League champions have already fallen one step behind Manchester United, Chelsea and Liverpool in the title race, but the visit of Norwich represents the ideal opportunity for Guardiola's men to get back on track.
Here, Sports Mole rounds up all of Man City's injury and suspension news ahead of the contest.
Type of injury: Foot
Possible return date: September 11 (vs. Leicester City)
Phil Foden sustained a foot injury en route to the Euro 2020 final with England, and Guardiola affirmed earlier this month that the attacker would be out for a "while", effectively ruling him out of this game.
Status: Major doubt
Type of injury: Ankle
Possible return date: August 21 (vs. Norwich City)
Guardiola revealed in his pre-match press conference that Kevin De Bruyne did not train on Friday morning due to a niggling ankle issue, leaving his participation on Saturday up in the air.
MAN CITY'S SUSPENSION LIST
City have no players suspended for this match.