The Spurs skipper missed the 2-1 defeat to Watford before the international break and was also forced to pull out of the France squad for their double-header against Germany and the Netherlands due to a thigh injury.
However, the 31-year-old - who is facing a drink-driving charge - could be back for the visit of Liverpool when domestic action resumes this weekend.
"I am working hard to get back as quickly as possible," Lloris told French radio station RMC.
"There may be a chance this weekend but we will see how much progress is made during the week."
Michel Vorm deputised for the World Cup winner during the loss to Watford in Tottenham's last Premier League outing.