Here, the PA news agency looks at their biggest Premier League losses.
October 4, 2020: Aston Villa 7 Liverpool 2
Sunday's walloping jumps to the top of the list, a defeat made all the more shocking by the fact the Reds are not only the reigning champions, but powered to the title in record time last season. Ollie Watkins opened the scoring after just four minutes and had a hat-trick before half-time. Jack Grealish added two and had a hand in three others. John McGinn and former Everton player Ross Barkley got the others with Jurgen Klopp's men netting twice through Mohamed Salah.
May 24, 2015: Stoke 6 Liverpool 1
Steven Gerrard's final game for Liverpool turned into a nightmare as the Merseysiders were thrashed by the Potters on the last day of the season. Stoke lead 5-0 at the break after a Mame Biram Diouf double and further efforts from Jonathan Walters, Charlie Adam and Steven Nzonzi. Gerrard did manage to get on the scoresheet but former Liverpool striker Peter Crouch had the final say.
September 9, 2017: Manchester City 5 Liverpool 0
Liverpool were already trailing 1-0 to a Sergio Aguero goal at the Etihad Stadium when Sadio Mane was sent off for a high challenge on goalkeeper Ederson. The afternoon then unravelled as City showed just how formidable a side they had become under Pep Guardiola. City powered to a convincing win with Gabriel Jesus and Leroy Sane both scoring two goals each.