Liverpool have been drawn to face Everton in the FA Cup third round, less than a week before the teams do battle at Anfield in the Premier League.
Manager Jurgen Klopp has previously used cup competitions to rotate his squad, but the German may now be forced to play his star names against the club's city rivals.
Premier League leaders Manchester City will host Burnley, while Manchester United have been handed a home meeting with Championship side Derby County.
Holders Arsenal must travel to the City Ground to face Nottingham Forest, while AFC Wimbledon will visit Wembley Stadium to take on Tottenham Hotspur.
Chelsea will travel to East Anglia to take on Norwich City, with fellow Championship side Wolverhampton Wanderers being drawn at home to play Swansea City.
Brighton & Hove Albion will take on rivals Crystal Palace at the Amex Stadium, and Middlesbrough and Sunderland will contest the North-East derby at the Riverside Stadium.
All of the ties will be played between January 5 and January 8.
Full draw
Ipswich Town vs. Sheffield United Watford vs. Bristol City Birmingham City vs. Burton Albion Liverpool vs. Everton Brighton & Hove Albion vs. Crystal Palace Aston Villa vs. Woking or Peterborough Bournemouth vs. AFC Fylde or Wigan Athletic Coventry City vs. Stoke City Newport County vs Leeds United Bolton Wanderers vs. Huddersfield Town Port Vale or Yeovil Town vs. Bradford City Nottingham Forest vs. Arsenal Brentford vs. Notts County Queens Park Rangers vs. MK Dons Manchester United vs. Derby County Forest Green Rovers or Exeter City vs. West Bromwich Albion Doncaster Rovers vs. Slough Town or Rochdale Tottenham Hotspur vs. AFC Wimbledon Middlesbrough vs. Sunderland Fleetwood Town or Hereford vs. Leicester City Blackburn Rovers or Crewe Alexandra vs. Hull City Cardiff City vs. Mansfield Town Manchester City vs. Burnley Shrewsbury Town vs. West Ham United Wolverhampton Wanderers vs. Swansea City Stevenage vs. Reading Newcastle United vs. Luton Town Millwall vs. Barnsley Fulham vs. Southampton Wycombe Wanderers vs. Preston North End Norwich City vs. Chelsea Gillingham or Carlisle United vs. Sheffield Wednesday