Ahead of the Serie A meeting on Monday night, both of these sides exited European competitions at the quarter-finals stage last week.
You could argue that the three points are needed more by hosts Lazio, who are under pressure from Inter Milan in the final Europa League place. What's more, a victory would draw them closer to a Champions League slot.
However, any positive result that they are able to collect would have to be achieved without the suspended trio of Giuseppe Biava, Stefan Radu and Senad Lulic, while Abdoulay Konko, Andre Dias and Bruno Pereirinha are all injured.
The Old Lady have lost just one of their last 10 meetings with Rome-based Lazio.
Possible starting lineups
Lazio: Marchetti; Gonzalez, Ciani, Cana, Stankevicius; Ledesma, Candreva, Mauri, Hernanes, Onazi; Klose
Juventus: Buffon; Barzagli, Bonucci, Peluso; Lichtsteiner, Vidal, Pirlo, Pogba, Asamoah; Matri, Vucinc
Sports Mole says: 2-1