Kazakhstan vs. France (Sunday, 2.00pm)
The hosts kick off their road to Qatar following some miserable results in 2020, while France could only take a point from their battle with Ukraine in midweek.
We say: Kazakhstan 0-4 France
France could hardly have a better opportunity to right the wrongs of midweek against a Kazakhstan side who did not cover themselves in glory last year. The return of Baysufinov may boost the confidence in the hosts' camp, but a shock home win seems out of the question and the champions should ease to a comfortable victory at the second time of asking in Group D.
Denmark vs. Moldova (Sunday, 5.00pm)
We say: Denmark 2-0 Moldova
Denmark will fancy their chances of putting another three points on the board ahead of their trip to Austria on March 31, and we can only see one result in this match. Moldova are capable of keeping the score down, but it should be a relatively comfortable 90 minutes of football for the home team.
Albania vs. England (Sunday, 5.00pm)
We say: Albania 0-2 England
Albania are not just here to make up the numbers - the grit and determination they showed to get over the line against Andorra means that they command respect from their visitors this weekend. However, most of Southgate's big-hitters will be well-rested and should have no trouble breaching Reja's defence, so we can only back a second triumph for the Three Lions.
Armenia vs. Iceland (Sunday, 5.00pm)
We say: Armenia 0-1 Iceland
Iceland have lost six games in a row and Armenia are unbeaten in the same number of matches, but that does not quite tell the whole story.
The visitors have faced some strong opposition over the past year and this represents a chance to get back to winning ways, which we are tipping them to do in Yerevan.
Georgia vs. Spain (Sunday, 5.00pm)
La Roja were held to a 1-1 draw by Greece in their group opener on Thursday, while Georgia opened their campaign with a 1-0 defeat against Sweden.
We say: Georgia 0-2 Spain
Spain were frustrated by Greece on Thursday, which could work against Georgia heading into this match. Enrique will be demanding a response from his players, and we are expecting the visitors to collect all three points in relatively routine fashion here.
Bulgaria vs. Italy (Sunday, 7.45pm)
The hosts, on the other hand, got off to a losing start against Switzerland, with a chastening 3-1 home defeat coming after racking up a three-goal deficit after just 13 minutes.
We say: Bulgaria 1-2 Italy
Though Italy are clearly a class apart from their next opponents in World Cup qualifying, coach Roberto Mancini may tinker with his team due to an intense schedule of three competitive games in a week.
Even if the visitors are not quick out of the blocks against their mediocre hosts on Sunday, there is an abundance of proven firepower for the Azzurri to call upon on the sidelines and they will surely seal six points from a possible six, ahead of another eminently winnable encounter with Lithuania in the coming days.
Switzerland vs. Lithuania (Sunday, 7.45pm)
Switzerland will be looking to make it back-to-back wins at the start of their 2022 World Cup qualification when they host Lithuania on Sunday night.
Vladimir Petkovic's side opened their Group C challenge with a 3-1 victory away to Bulgaria on Thursday, while Lithuania suffered a 4-0 defeat to Kosovo in a friendly on Wednesday.
We say: Switzerland 3-0 Lithuania
Lithuania are going to find it very difficult to make an impression in Group C, and they face a very tough assignment away to a talented Switzerland on Sunday. The home side will be in a confident mood following their win in Bulgaria, and we are expecting them to put another three points on the board here.
Ukraine vs. Finland (Sunday, 7.45pm)
Ukraine will be looking to build on their impressive point away to France when they host Finland in their second World Cup 2022 qualifying fixture.
The Yellow and Blue held the world champions 1-1 in Paris on Wednesday, while Finland played out a 2-2 draw with Bosnia-Herzegovina in their opening Group D match.
We say: Ukraine 2-1 Finland
Ukraine picked up a good point in Paris in their opening group game and went unbeaten in their last qualifying campaign.
Finland are coming off the back of a largely positive Nations League campaign, meanwhile, but they are 31 places below their opponents in the FIFA rankings and we expect that to show on Sunday.
Austria vs. Faroe Islands (Sunday, 7.45pm)
Austria play host to the Faroe Islands on Sunday evening as they look to extend their unbeaten start to Group F.
Franco Foda's side opened their World Cup qualifying campaign with a 2-2 draw in Scotland, while the visitors earned a share of the spoils against Moldova.
We say: Austria 3-0 Faroe Islands
Despite the likelihood of changes being made for this game, we still expect Austria to come through with minimal fuss. Although the visitors will take confidence from Thursday's result, they do not possess the quality to trouble their in-form opponents.
Israel vs. Scotland (Sunday, 7.45pm)
Israel and Scotland renew their recent rivalry on Sunday evening as they bid to record their first victory in Group F.
While Scotland earned a 2-2 draw at home to Austria, Israel started their World Cup qualifying campaign with a 2-0 reverse against Denmark.
We say: Israel 1-1 Scotland
While both teams will want to try to keep pace with Denmark and Austria, they will also acknowledge that they can ill-afford a defeat on Sunday. With that in mind, we expect a low-key share of the spoils, a result which would benefit Scotland more so than Israel.
Poland vs. Andorra (Sunday, 7.45pm)
Poland will host Andorra in their second World Cup 2022 qualifier on Sunday evening hoping to record their first victory in Group I.
The hosts head into this fixture after drawing a six-goal thriller away in Hungary on Thursday, while the visitors narrowly lost to Albania on home soil.
We say: Poland 5-0 Andorra
Poland will feel that Sunday's fixture at home to Andorra is the perfect way for them to bounce back from their midweek draw in Budapest.
Sousa's side have plenty of firepower, and they should have no issues in securing a commanding victory in Warsaw, which would extend Andorra's 13-game winless run.
San Marino vs. Hungary (Sunday, 7.45pm)
Hungary will travel to European minnows San Marino in their second World Cup 2022 qualifier on Sunday evening hoping to record their first victory in Group I.
The visitors head into this fixture after drawing a six-goal thriller against Poland on Thursday, while the hosts were beaten heavily by England at Wembley Stadium.
We say: San Marino 0-5 Hungary
San Marino have not managed to avoid defeat in a World Cup qualification game since holding Latvia to a 1-1 draw in 2001, and their chances of replicating such a result against Hungary are slim.
The visitors should have no problems in securing a comfortable victory at the Stadio Olimpico di Serravalle on Sunday.
N. Macedonia vs. Liechtenstein (Sunday, 7.45pm)
After opening their Qatar 2022 qualifying campaign with a tumultuous 3-2 defeat in midweek, European Championship finalists North Macedonia take on the tiny principality of Liechtenstein in Skopje on Sunday.
The 181st-ranked visitors were also beaten by a late goal in the first fixture of what is set to be another challenging campaign for the Central European minnows, as the Group G action continues apace.
We say: North Macedonia 2-0 Liechtenstein
Certainly strong favourites to put their first three points on the board in pursuit of a place at Qatar 2022, North Macedonia should seal the win by at least two clear goals, but may not enjoy a free-for-all against dogged visitors who have conceded only three times in their last five outings - albeit versus mostly modest opposition.
With a smattering of quality from the top five European leagues to call upon, the Red Lions can put Liechtenstein to the sword before focusing on a far tougher encounter with Germany in the coming days.
Romania vs. Germany (Sunday, 7.45pm)
Romania and Germany will both aspire to record back-to-back wins in World Cup Qualifying Group J when they lock horns at the Arena Nationala in Bucharest this Sunday.
The hosts scraped a dramatic 3-2 win over North Macedonia in their opening fixture, while Germany also chalked up a trio of goals in a routine 3-0 win over Iceland.
We say: Romania 1-3 Germany
Romania need not take any lessons on how to find the back of the net at home - 11 goals from their last three outings on familiar territory is evidence of their goalscoring prowess. However, coming up against a well-drilled German defence - coupled with several bright young attacking stars - spells trouble for the hosts, and we can only envisage another win for Germany in Group J.
Kosovo vs. Sweden (Sunday, 7.45pm)
Sweden face Kosovo on Sunday evening with the opportunity to maintain their position at the top of Group B.
While the visitors kicked off their World Cup qualifying campaign with a narrow win over Georgia, Kosovo thrashed Lithuania by a 4-0 scoreline in a friendly.
We say: Kosovo 1-2 Sweden
Even with the reintroduction of Ibrahimovic, goals may not be forthcoming for this Sweden side. Nevertheless, we still expect the visitors to use their big-match experience to good effect, edging out their hosts in a competitive contest.