However, Newcastle have beaten Chelsea in three of the last four meetings between the sides, including a 2-0 victory at St James' Park in November, courtesy of goals from Loic Remy and Yoan Gouffran.
It will be a much different Magpies side that faces them on Saturday, though, with both the aforementioned Frenchman and the now-departed Yohan Cabaye not available to Alan Pardew, who will be looking for a response from his players following the 3-0 Tyne-Wear derby defeat to Sunderland.
Luuk de Jong, the only January arrival brought in by Joe Kinnear, who quit his role as Newcastle director of football this week, may be handed his first start due to the shortage of forward options.
Mourinho has far fewer selection issues, but is likely to recall Oscar to form a more attacking midfield. Considering Nemanja Matic's seamless return to English football with a man-of-the-match display against City, it may be David Luiz that drops out, with Ramires shifted back to the centre.