West Brom vs. Everton (Thursday, 6.00pm)
Both teams scraped 1-0 victories in their most recent outings, with West Brom controversially overcoming Brighton & Hove Albion while Champions League hopefuls Everton beat Southampton by the same scoreline.
We say: West Bromwich Albion 1-2 Everton
West Brom and Everton will both have their tails up heading into this showdown, but changes on both ends are to be expected given the crunch matches they face at the weekend. With the prospect of Everton welcoming back three key outfield players for this battle - as well as their remarkable away record - we expect the Toffees to continue their Champions League charge with a slender victory on Thursday, but Allardyce's men are sure to put up a good fight.
Fulham vs. Spurs (Thursday, 6.00pm)
We say: Fulham 0-1 Tottenham Hotspur
Any significant alterations to either team will have a major impact on the outcome of this match, and both Parker and Mourinho have several big calls to make during a hectic week. The Cottagers' defensive resilience will be tested to the limit against Bale and co on Thursday, and while Mourinho's side are unlikely to have as much joy in front of goal as they did against Wolfsberger and Burnley, we still expect Spurs to eke out a vital win in a closely-fought battle.
Liverpool vs. Chelsea (Thursday, 8.15pm)
The hosts sit one place and one point behind their visitors, and victory for either team would be enough to lift them into the Champions League spots with fourth-placed West Ham United not in action in midweek.
We say: Liverpool 1-1 Chelsea
The last time Chelsea visited Anfield there were goals galore and Liverpool ended the night by lifting the Premier League trophy aloft. Thursday's showdown is likely to be very different.
The fortress that was Anfield has been destroyed in the space of four games, while it is difficult to see this Chelsea team shipping five goals under Tuchel given the watertight start they have made since the new boss took over.
There have only been three goalless draws between these two sides in the Premier League era, so goals are likely, but while a top-four spot awaits the winner, defeat would be a huge blow for either side's Champions League hopes and we therefore expect this one to end all square.