A much improved second-half performance from Sevilla was not enough to gain a point against Celta Vigo as first-half goals from Nolito and Daniel Wass proved enough for Eduardo Barizzo's men to claim another victory.
Moments after Wass had struck a warning shot just over Sevilla's crossbar, Nolito opened the scoring for Celta Vigo, beating centre-half Mariano before finding the bottom corner.
Sevilla, having already introduced Michael Krohn-Dehli after 30 minutes, brought on former Juventus striker Fernando Llorente at half time for Ever Banega which resulted in a formation switch to 4-4-2.
The change in personnel produced instant rewards for Unai Emery's men as Mariano's cross found Llorente at the back post, the substitute making no mistake with his header.
Krohn-Dehli then attempted to make it two scoring substitutes from two but his long-range effort struck Sergio Alvarez's crossbar.
Celta, who were pinned back by their opponents for much of the second period, went close through Iago Aspas but Rico got a strong hand to the Celta forward's effort.
The home side continued to pressure Celta, having several penalty appeals rejected by the referee, but they were unable to find an equaliser.