Jose Cubero is yet to make his debut for the Tangerines because of work permit issues and a knee injury, but both issues could be resolved by the weekend.
Andrea Orlandi may miss the chance to play against his former club as he has been struggling with a foot injury, which forced him to miss Tuesday's defeat to Watford.
Meanwhile, Brighton have been in mixed form in recent weeks, with two wins, two defeats and a draw in their last five matches.
The hosts may be boosted by the return of Paddy McCourt, who came through 90 minutes with the club's Under-21s earlier this week after picking up an ankle injury while on trial with the club in pre-season.
When the teams met in Brighton last season, the two sides shared a 1-1 draw, with Blackpool's last win against the Seagulls coming in March 2012.
Possible starting lineups
Brighton: Stockdale, Greer, Bruno, Bennett, Dunk, Forster-Caskey, Ince, Mackail-Smith, Teizeira, Lua Lua, Baldock
Blackpool: Lewis, Oriol, Clarke, McMahon, Daniels, Ranger, Perkins, Delfouneso, Lundstram, Cywka, Miller
Sports Mole says: 1-3