The 18-year-old joined the Midlands outfit on loan from AS Monaco over the summer and impressed during the side's 2-0 victory at Premier League Southampton on Wednesday night, earning him a place in Nuno Espirito Santo's starting XI today.
Barry Douglas is the man to make way as Wolves look to bounce back from their 2-1 home defeat to Championship leaders Cardiff City last Saturday following an impressive start to the season.
Ben Marshall made a surprise appearance for Wolves on the south coast following time out with injury but is rested today as the likes of Ivan Cavaleiro, Nouha Dicko and youngster Connor Ronan make the bench.
Dave Edwards, linked with a move to rivals Reading, is omitted from the matchday squad.
For the visitors, Dean Smith is able to name Jota in his starting XI following his recovery from a back injury.
The rock-bottom hosts are otherwise unchanged from the 2-0 defeat at Ipswich Town last week, with Smith expected to again play a 4-2-3-1 formation.
Brentford: Bentley; Dalsgaard, Dean, Colin, Barbet; Mokotjo, Yennaris; Sawyers, Jota, Watkins; Maupay
Subs: Daniels, Bjelland, Jozefzoon, Egan, Woods, Clarke, Canos
Wolverhampton Wanderers: Ruddy; Miranda, Coady, Boly; Doherty, Saiss, Neves, Vinagre; Enobakhare, Bonatini, Jota
Subs: Norris, Bennett, Batth, Cavaleiro, Dicko, Price, Ronan