The 24-year-old's initial three-match ban was reduced to two on Friday, meaning that the striker will start up front for the defending German champions this afternoon.
Julian Schieber will partner Lewandowski in attack.
Borussia Dortmund: Weidenfeller; Subotic, Grosskreutz, Santana,
Schmelzer; Kehl, Gundogan, Reus, Blaszczykowski; Lewandowski, Schieber
Hannover: Zieler; Djourou, Pocognolli, Schulz, Chahed; Pinto, Ya Konan, Hoffmann, Rausch; Sobiech, Abdellaoue